Solution:

Note $m = \sqrt{n^2 - 49} \ge 0$ has to be an integer, so $n^2 - 49 = m^2,$ which means $(n - m)(n + m) = 49.$ The factorizations of $49$ give $|n| = 25, m = 24$ or $|n| = 7, m = 0.$ So the ordered pairs $(m, n)$ are $(24, 25),$ $(24, -25),$ $(0, 7),$ $(0, -7).$ That's $4$ of them. Thus, D is the correct answer.